Effect of biscuit formulations in the release of satiety hormones

Authors

  • Nuria Martinez-Saez CIAL, Instituto de Investigación de Ciencias de la Alimentación (UAM-CSIC), Madrid, España
  • Christina Maria Hochkogler Departamento de Química Nutricional y Fisiológica, Facultad de Química, Universidad de Viena, Austria
  • Veronika Somoza Departamento de Química Nutricional y Fisiológica, Facultad de Química, Universidad de Viena, Austria
  • María Dolores del Castillo CIAL, UAM-CSIC

DOI:

https://doi.org/10.26461/11.09

Keywords:

Antioxidant coffee fibre, FOS, GLP-1, low glycaemic index, serotonin, stevia

Abstract

This research aimed to evaluate the potential of a new biscuit formulation with low glycaemic index and high sensorial quality for an effective control of satiety. Stevia as hypocaloric sweetener, fructooligosaccharides (FOS) as enhancer of glucose tolerance and sensorial quality, and antioxidant insoluble dietary fibre (spent coffee grounds) were used as food ingredients. Food and individual ingredients were digested in vitroby mimicking human oral-gastrointestinal digestion. The in vitrorelease of glucagon-like petide-1 (GLP-1) and serotonin was stimulated by incubation of human intestinal cells, HuTu-80 and Caco-2, with digests at final concentrations of 0,5, 0,05 and 0,01 mg/ml, for 90 min and 5 min, respectively. Quantification of the hormones called as GLP1 and serotonin was carried out by ELISA. The traditional and new biscuits induced the release of hormones in the same order of magnitude (p>0,05). Antioxidant coffee fibre contributed to stimulate the release of satiety hormones while stevia was ineffective. Replacement of sucrose by stevia did not affect the satiating capacity of the biscuit. In conclusion, a new healthy food containing high level of antioxidant dietary fibre, satiating, good sensorial quality for healthy people and friendly for diabetics has been obtained.

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References

Anton, S, Martin, C, Han, H, Coulon, S, Cefalu, W, Geiselman, P y Williamson, D, 2010. Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. En: Appetite, 55(1), pp.37–43.

Bakuradze, T, Parra, G, Riedel, A, Somoza, V, Lang, R, Dieminger, N y Richling, E, 2014. Four-week coffee consumption affects energy intake, satiety regulation, body fat, and protects DNA integrity. En: Food Research International, 63, pp.420-427.

Choi, S, DiSilvio, B, Fernstrom, M y Fernstrom, J, 2009. Meal ingestion, amino acids and brain neurotransmitters: Effects of dietary protein source on serotonin and catecholamine synthesis rates. En: Physiology and Behavior, 98(1-2), pp.156–162.

Choi, S, DiSilvio, B, Fernstrom, M y Fernstrom, J, 2011. The chronic ingestion of diets containing different proteins produces marked variations in brain tryptophan levels and serotonin synthesis in the rat. En: Neurochemical Research, 36(3), pp.559–565.

del Castillo, M., Martinez-Saez, N. y Ullate, M., 2014. Healthy bakery products with high level of dietary antioxidant fibre. Patente española. PCT/ES2014/070062.

Delzenne, N, Cani, P y Neyrinck, A, 2007. Modulation of Glucagon-like Peptide 1 and Energy Metabolism by Inulin and Oligofructose: Experimental Data. En: Journal of Nutrition, 137(11), pp.2547S–2551S.

Edwards, A y Slater, N, 2009. Protection of live bacteria from bile acid toxicity using bile acid adsorbing resins. En: Vaccine, 27(29), pp.3897–3903.

EFSA, 2014. Scientific Opinion on the substantiation of a health claim related to non-digestible carbohydrates and a reduction of post-prandial glycaemic responses pursuant to Article 13 (5) of Regulation (EC) No 1924/2006. En: EFSA Journal, 12(1), pp.1–13.

Frost, G, Brynes, A, Dhillo, W, Bloom, S y McBurney, M, 2003. The effects of fiber enrichment of pasta and fat content on gastric emptying, GLP-1, glucose, and insulin responses to a meal. En: European Journal of Clinical Nutrition, 57, pp.293–298.

Fujii, Y, Osaki, N, Hase, T y Shimotoyodome, A, 2015. Ingestion of coffee polyphenols increases postprandial release of the active glucagon-like peptide-1 (GLP-1(7–36)) amide in C57BL/6J mice. En: Journal of Nutritional Science, 4, (e9), pp.1-9.

Fujita, Y, Wideman, R, Speck, M, Asadi, A, King, D, Webber, T y Kieffer, T, 2009. Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. En: American Journal of Physiology. Endocrinology and Metabolism, 296(3), pp.E473–E479.

Garcia-Serna, E, Martinez-Saez, N, Mesias, M, Morales, F, y del Castillo, M, 2014. Use of coffee silverskin and stevia to improve the formulation of biscuits. En: Polish Journal of Food and Nutrition Sciences, 64(4), pp.243–251.

Geraedts, M, Troost, F, Fischer, M, Edens, L y Saris, W, 2011. Direct induction of CCK and GLP-1 release from murine endocrine cells by intact dietary proteins. En: Molecular Nutrition and Food Research, 55(3), pp.476–484.

Geraedts, M., Troost, F, Tinnemans, R, Söderholm, J, Brummer, R y Saris, W, 2010. Release of satiety hormones in response to specific dietary proteins is different between human and murine small intestinal mucosa. En: Annals of Nutrition and Metabolism, 56(4), pp.308–313.

Gostner, J, Schroecksnadel, S, Jenny, Klein, A, Ueberall, F, Schennach, H y Fuchs, D, 2015. Coffee Extracts Suppress Tryptophan Breakdown in Mitogen-Stimulated Peripheral Blood Mononuclear Cells. En: Journal of the American College of Nutrition, 34(3), pp.212–223.

Grover, G, Koetzner, L, Wicks, J, Gahler, R, Lyon, M, Reimer, R y Wood, S, 2011. Effects of the soluble fiber complex PolyGlycopleX® (PGX®) on glycemic control, insulin secretion, and GLP-1 levels in Zucker diabetic rats. En: Life Sciences, 88(9-10), pp.392–399.

Habib, N, Honoré, S, Genta, S y Sánchez, S, 2011. Hypolipidemic effect of Smallanthus sonchifolius (yacon) roots on diabetic rats: Biochemical approach. En: Chemico-Biological Interactions, 194(1), pp.31–39.

Hellfritsch, C, Brockhoff, A, Stähler, F, Meyerhof, W y Hofmann, T, 2012. Human psychometric and taste receptor responses to steviol glycosides. En: Journal of Agricultural and Food Chemistry, 60(27), pp.6782–6793.

Herrera, C, Smith, K, Atkinson, F, Ruell, P, Chow, C, O’Connor, H y Brand-Miller, J, 2011. High-glycaemic index and -glycaemic load meals increase the availability of tryptophan in healthy volunteers. En: The British Journal of Nutrition, 105(11), pp.1601–1606.

Holik, A, Rohm, B, Somoza, M y Somoza, V, 2013. N(ε)-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells. En: Food and Function, 4(7), pp.1111–20.

Hollebeeck, S, Borlon, F, Schneider, Y, Larondelle, Y y Rogez, H, 2013. Development of a standardised human in vitrodigestion protocol based on macronutrient digestion using response surface methodology. En: Food Chemistry, 138(2-3), pp.1936–1944.

Huang, W, Chen, Z, Wang, Q, Lin, M, Wu, S, Yan, Q y Pan, J, 2013. Piperine potentiates the antidepressant-like effect of trans-resveratrol: Involvement of monoaminergic system. En: Metabolic Brain Disease, 28(4), pp.585–595.

Ishwarya, S, y Prabhasankar, P, 2013. Fructooligosaccharide – Retention during baking and its influence on biscuit quality. En: Food Bioscience, 4, pp.68–80.

Jokura, H, Watanabe, I, Umeda, M, Hase, T y Shimotoyodome, A, 2015. Coffee polyphenol consumption improves postprandial hyperglycemia associated with impaired vascular endothelial function in healthy male adults. En: Nutrition Research, 35(10), pp.873–881.

Kumar, V, Sinha, A, Makkar, H, de Boeck, G y Becker, K, 2012. Dietary Roles of Non-Starch Polysachharides in Human Nutrition: A Review. En: Critical Reviews in Food Science and Nutrition, 52(10), pp.899–935.

Lee, C. Y, 2016. Glucagon-like Peptide-1 Formulation - the Present and Future Development in Diabetes Treatment. En: Basic and Clinical Pharmacology and Toxicology, 118, pp.173–180.

Li, P, Lin, W, Wang, Y, Peng, W, Cai, X y Su, W, 2012. Antidiabetic activities of oligosaccharides of Ophiopogonis japonicus in experimental type 2 diabetic rats. En: International Journal of Biological Macromolecules, 51(5), pp.749–755.

Liu, Y, Lan, N, Ren, J, Wu, Y, Wang, S-T, Huang, X y Yu, Y, 2015. Orientin improves depression-like behavior and BDNF in chronic stressed mice. En: Molecular Nutrition and Food Research, 59, pp.1130–1142.

Manning, P, Sutherland, W, Manning, A, de Jong, S y Berry, E, 2013. Ingestion of thermally oxidized sunflower oil decreases postprandial lipemia mainly in younger individuals. En: Nutrition Research, 33(9), pp.711–718.

Mawe, G y Hoffman, J, 2013. Serotonin Signaling in the Gastrointestinal Tract: Functions, dysfunctions, and therapeutic targets. En: Nature Reviews Gastroenterology and Hepatology, 10(8), pp.473–486.

McCarty, M, 2005. A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk. En: Medical Hypotheses, 64(4), pp.848–853.

Nutritional Heart, Lung, and Blood Institute, 2013. Managing overweight and obesity in adults: systematic evidence review from the obesity expert panel. Washington: U.S Department of Health and Human Services.

Rafferty, E, Wylie, A, Elliott, C, Chevallier, O, Grieve, D y Green, B, 2011. In vitro and in vivo effects of natural putative secretagogues of Glucagon-like peptide-1 (GLP-1). En: Scientia Pharmaceutica, 79(3), pp.615–621.

Unión Europea. Reglamento (CE) 1924/2006, de 20 de diciembre de 2006. Official Journal of the European Union, 30 de diciembre de 2006, No. L404/9.

Sartori da Silva, A, Haas, P, Sartori, N, Anton, A y Francisco, A, 2007. Fructoligosaccharides: active dietary fibers. En: Boletim Do Centro de Pesquisa E Processamento de Alimentos, 25(2), pp.295–304.

Sharma, R, Yadav, R, y Manivannan, E, 2012. Study of effect of Stevia rebaudiana bertoni on oxidative stress in type-2 diabetic rat models. En: Biomedicine and Aging Pathology, 2(3), pp.126–131.

Tamanna, N y Mahmood, N, 2015. Food processing and maillard reaction products: effect on human health and nutrition. En: International Journal of Food Science, 2015, pp.1–6.

Van Bloemendaal, L, IJzerman, R, Ten Kulve, J, Barkhof, F, Konrad, R, Drent, M y Diamant, M, 2014. GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans. En: Diabetes, 63(12), pp.4186–4196.

Voigt, J y Fink, H, 2015. Serotonin controlling feeding and satiety. En: Behavioural Brain Research, 277, pp.14–31.

World Health Organization, 2014. Global satus report on noncommunicable diseases 2014 [En línea]. Geneva: WHO. [Consulta: 14 de abril de 2016] Disponible en: http://www.who.int/mediacentre/factsheets/fs311/es/#.

Zelkas, L, Raghupathi, R, Lumsden, A., Martin, A, Sun, E, Spencer, N y Keating, D, 2015. Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability. En: Nutrition and Metabolism, 12(1), pp.55.

Published

2016-07-08

How to Cite

Martinez-Saez, N., Hochkogler, C. M., Somoza, V., & del Castillo, M. D. (2016). Effect of biscuit formulations in the release of satiety hormones. INNOTEC, 1(11 ene-jul), 65–72. https://doi.org/10.26461/11.09

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